Cell Meter APC-Annexin V細胞凋亡檢測試劑盒是美國AAT Bioquest生產(chǎn)的用于細胞凋亡的試劑盒，膜聯(lián)蛋白V可以與包括APC的熒光染料綴合。保留了其對磷脂酰絲氨酸（PS）的高親和力，因此可作為流式細胞儀分析細胞凋亡的靈敏探針。

數(shù)據(jù)分析

        在活的非凋亡細胞中，APC-膜聯(lián)蛋白V檢測非誘導細胞中的先天性細胞凋亡，其通常為所有細胞的2-6％。 在凋亡細胞中，APC-膜聯(lián)蛋白V與磷脂酰絲氨酸結(jié)合，磷脂酰絲氨酸位于細胞膜的外葉上，因此導致染色強度增加。

參考文獻

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Ubiquitin ligase CHIP functions as an oncogene and activates the AKT signaling pathway in prostate cancer
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